PubAg

Main content area

For Certain, SIRT4 Activities!

Author:
Kumar, Surinder, Lombard, David B.
Source:
Trends in biochemical sciences 2017 v.42 no.7 pp. 499-501
ISSN:
0968-0004
Subject:
enzyme activity, leucine, lysine, metabolism
Abstract:
Despite the fact that SIRT4 regulates important biological processes, its primary enzymatic activity has remained ambiguous. A recent study by Anderson, Huynh et al. has uncovered deacylase activities of SIRT4 towards newly described lysine modifications derived from reactive acyl-CoAs generated in leucine catabolism.
Agid:
5730626