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Age of initial cohort of dengue patients could explain the origin of disease outbreak in a setting: a case control study in Rajasthan, India

Angel, Annette, Angel, Bennet, Yadav, Karuna, Sharma, Neha, Joshi, Vinod, Thanvi, Indu, Thanvi, Sharad
VirusDisease 2017 v.28 no.2 pp. 205-208
Aedes aegypti, adults, breeding, case-control studies, children, containers, dengue hemorrhagic fever, disease outbreaks, disease transmission, hospitals, households, humans, immunoglobulin G, immunoglobulin M, immunologic techniques, larvae, patients, public health, retrospective studies, schools, vector control, India
Dengue fever (DF) and dengue hemorrhagic fever (DHF) is a public health problem with 390 million cases reported in world annually. In Rajasthan, DF with DHF is being reported for about two decades. For undertaking interventions into disease transmission, locating origin of transmission is very important. Present paper reports retrospective analysis of the hospital reported cases of dengue during the year 2013–2014 undertaken in Barmer, Rajasthan. To address task of investigating outbreak, detailed analysis of the data on serological test results (Mac-ELISA assay of NS1, IgG and IgM) performed by local hospital, Balotra was made. The domestic breeding containers were examined for the presence of larvae and adult forms of Aedes aegypti by visiting individual households as well as common places of human aggregation like schools and hospitals. The analysis showed that first dengue cases started from the lot of school going children and then followed by adults and finally during peak period of infection only children around 1–2 years got infected. The subsequent entomological investigations during the outbreak showed school as principal source of mosquito breeding. Present investigations highlight that schools (March to April) play the role of primary sites of disease transmission and should be preferred for undertaking vector control operations to prevent dengue transmission from getting aggravated.