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First complete genome sequence of a virulent bacteriophage infecting the opportunistic pathogen Serratia rubidaea
- Xing, Shaozhen, Ma, Taping, Zhang, Xianglilan, Huang, Yong, Mi, Zhiqiang, Sun, Qiang, An, Xiaoping, Fan, Hang, Wu, Shuhui, Wei, Lin, Tong, Yigang
- Archives of virology 2017 v.162 no.7 pp. 2021-2028
- DNA, Klebsiella, Myoviridae, Serratia rubidaea, bacteriophages, genome, high-throughput nucleotide sequencing, hospitals, nucleotide sequences, nucleotides, secondary infection, sewage, virulence
- A Serratia rubidaea phage, vB_Sru IME250, was isolated from hospital sewage. The morphology suggested that phage vB_Sru IME250 should be classified as a member of the family Myoviridae. High-throughput sequencing revealed that the phage genome has 154,938 nucleotides and consists of 193 coding DNA sequences, 90 of which have putative functions. The genome of vB_Sru IME250 is a linear, double-stranded DNA with an average GC content of 40.04%. The phage has a relatively high similarity to Klebsiella phage 0507-KN2-1, with a genome coverage of 84%.