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Pulmonary vascular remodeling in pulmonary hypertension
- Tuder, Rubin M.
- Cell and tissue research 2017 v.367 no.3 pp. 643-649
- animal pathology, hypertension, lungs, pathogenicity
- Pulmonary vascular remodeling is the key structural alteration in pulmonary hypertension and involves changes in the intima, media and adventitia, often with the interplay of inflammatory cells. This review examines the pathology of these changes and highlights some of the pathogenetic mechanisms that underlie the remodeling process.