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Boron–Heck Reaction of Cyclic Enaminones: Regioselective Direct Arylation via Oxidative Palladium(II) Catalysis

Author:
Kim, Yong Wook, Georg, Gunda I.
Source:
Organic letters 2014 v.16 no.6 pp. 1574-1577
ISSN:
1523-7052
Subject:
acids, arylation, catalytic activity, chemical structure, organic compounds, palladium, regioselectivity
Abstract:
An oxidative boron–Heck reaction of cyclic enaminones with arylboronic acids is reported. This protocol provides a regioselective arylation at the C6 position of cyclic enaminones. When an N-carbamylated cyclic enaminone was employed, a switch to a conjugate addition reaction occurred in the presence of acid.
Agid:
5788363