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Chemiluminescence Sensing of Fluoride Ions Using a Self-Immolative Amplifier
- Turan, Ilke Simsek, Akkaya, Engin U.
- Organic letters 2014 v.16 no.6 pp. 1680-1683
- aqueous solutions, chemical reactions, chemical structure, chemiluminescence, fluorides, glass, ions, polymethylmethacrylate
- An enhanced chemiluminescence signal is obtained when electronically triggered dioxetane cleavage is initiated by fluoride-mediated deprotection of the silyl-protecting group, followed by self-immolation via 1,4-quinone–methide rearrangement. The reaction takes place even when the probe is trapped within a PMMA layer on top of a glass plate. In that arrangement, fluoride in aqueous solutions can be detected selectively at low micromolar concentrations.