Jump to Main Content
Regioselective Synthesis of Vinyl Halides, Vinyl Sulfones, and Alkynes: A Tandem Intermolecular Nucleophilic and Electrophilic Vinylation of Tosylhydrazones
- Ojha, Devi Prasan, Prabhu, Kandikere Ramaiah
- Organic letters 2015 v.17 no.1 pp. 18-21
- Lewis acids, Lewis bases, alkynes, carbenes, carbon, chemical reactions, chemical structure, diazo compounds, organic halogen compounds, regioselectivity
- A diazo species is trapped in an intermolecular fashion by two independent ion species in tandem at the carbene center to install an electrophile and a nucleophile on the same carbon. This metal-free concept, which is unprecedented, has been illustrated by regioselective synthesis of a variety of vinyl halides, vinyl sulfones, and alkyne derivatives.