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Four-Component Approach to N-Substituted Phenothiazines under Transition-Metal-Free Conditions

Author:
Chen, Jinjin, Li, Guozheng, Xie, Yanjun, Liao, Yunfeng, Xiao, Fuhong, Deng, Guo-Jun
Source:
Organic letters 2015 v.17 no.23 pp. 5870-5873
ISSN:
1523-7052
Subject:
amines, chemical reactions, chemical structure, cyclohexanones, dimethyl sulfoxide, oxygen, phenothiazines, sulfur
Abstract:
An efficient synthesis of N-substituted phenothiazines has been developed from readily available amines, cyclohexanones, and elemental sulfur. The combination use of KI/DMSO in an oxygen atmosphere significantly improved the reaction yields.
Agid:
5789982