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Four-Component Approach to N-Substituted Phenothiazines under Transition-Metal-Free Conditions
- Chen, Jinjin, Li, Guozheng, Xie, Yanjun, Liao, Yunfeng, Xiao, Fuhong, Deng, Guo-Jun
- Organic letters 2015 v.17 no.23 pp. 5870-5873
- amines, chemical reactions, chemical structure, cyclohexanones, dimethyl sulfoxide, oxygen, phenothiazines, sulfur
- An efficient synthesis of N-substituted phenothiazines has been developed from readily available amines, cyclohexanones, and elemental sulfur. The combination use of KI/DMSO in an oxygen atmosphere significantly improved the reaction yields.