PubAg

Main content area

Palladium-Catalyzed α-Arylation of Enones in the Synthesis of 2-Alkenylindoles and Carbazoles

Author:
Kale, Ajit Prabhakar, Kumar, Gangam Srikanth, Mangadan, Arun Raj Kizhakkayil, Kapur, Manmohan
Source:
Organic letters 2015 v.17 no.5 pp. 1324-1327
ISSN:
1523-7052
Subject:
carbazoles, catalytic activity, chemical reactions, chemical structure, ethers, palladium, regioselectivity
Abstract:
A new unified strategy has been developed for the synthesis of substituted 2-alkenylindoles and carbazoles. The strategy uses palladium-catalyzed α-arylation of TES-enol ethers of enones as the key step. The method is highly regioselective, provides good yields, and is expected to have wide application.
Agid:
5790310