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Prevalence of Pneumocystis jirovecii among immunocompromised patients in hospitals of Tehran city, Iran

Homayouni, Mohammad Mohsen, Behniafar, Hamed, Mehbod, Amir Sayed Ali, Mohammad-Sadeghi, Mohammad-Javad, Maleki, Bahman
Journal of parasitic diseases 2017 v.41 no.3 pp. 850-853
Hodgkin disease, Pneumocystis, acquired immunodeficiency syndrome, fluorescent antibody technique, hospitals, immunocompromised population, non-Hodgkin lymphoma, parasitoses, patients, people, pneumonia, Iran
Pneumocystis jirovecii is an opportunistic organism that can cause extreme complications such as Pneumocystis pneumonia in immunocompromised individuals. There is no comprehensive study was conducted Iran to determine the prevalence of this infection in susceptible individuals. In the present study, 160 sera samples were collected from immunocompromised patients, including acquired immunodeficiency syndrome (AIDS) patients, diabetic patients, Hodgkin lymphoma patients and non-Hodgkin lymphoma patients. The specimens were collected from Imam Khomeini and army’s 501 hospitals. The specimens were examined using indirect fluorescent antibody test. The results of the study showed that 39.30% specimens were found positive, with different rates in different groups, including 20, 22.50, 37.50, and 77.50% of diabetic patients, non-Hodgkin patients, Hodgkin lymphoma patients, and AIDS patients, respectively. This occurrence is relatively high and can be a potential life-threatening hazard to infected patients in studied groups, on the other hand the organism can be transmitted from infected people to other susceptible individuals.