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Copper-Catalyzed Denitrogenative Transannulation Reaction of Pyridotriazoles: Synthesis of Imidazo[1,5-a]pyridines with Amines and Amino Acids
- Joshi, Abhisek, Chandra
Mohan, Darapaneni, Adimurthy, Subbarayappa
- Organic letters 2016 v.18 no.3 pp. 464-467
- amines, amino acids, chemical reactions, moieties, pyridines
- The copper-catalyzed aerobic oxidative synthesis of imidazo[1,5-a]pyridines via cascade denitrogenative transannulation reaction of pyridotriazoles with benzylamines with good functional group tolerance is developed. The present methodology is also applicable to amino acids to obtain imidazo[1,5-a]pyridines via decarboxylative oxidative cyclization.