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Photoinduced Vitamin B12-Catalysis for Deprotection of (Allyloxy)arenes

Author:
Giedyk, Maciej, Turkowska, Joanna, Lepak, Sandra, Marculewicz, Marcin, ó Proinsias, Keith, Gryko, Dorota
Source:
Organic letters 2017 v.19 no.10 pp. 2670-2673
ISSN:
1523-7052
Subject:
Lewis acids, aromatic hydrocarbons, chemical reactions, chemical structure, cobalt, photochemistry
Abstract:
Vitamin B₁₂ is a natural cobalt complex that, while reduced to the “supernucleophilic” Co(I) form, can easily react with electrophiles via an SN2 mechanism. It is also shown to react via an SN2′ mechanism with allylic compounds allowing for photochemical deprotection of (allyloxy)arenes. A sustainable alternative to commonly used noble metal-catalyzed deprotection reactions is presented.
Agid:
5792882