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Click and Release: SO2 Prodrugs with Tunable Release Rates

Author:
Ji, Xingyue, El-labbad, Eman M., Ji, Kaili, Lasheen, Deena S., Serya, Rabah A. T., Abouzid, Khaled A., Wang, Binghe
Source:
Organic letters 2017 v.19 no.4 pp. 818-821
ISSN:
1523-7052
Subject:
chemical structure, cycloaddition reactions, half life, organic compounds, sulfur dioxide
Abstract:
Employing an intramolecular cycloaddition reaction, we have developed a series of SO₂ prodrugs with tunable release rates with half-lives ranging from minutes to days.