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Reduced Graphene Oxide-Modified Screen-Printed Carbon (rGO-SPCE)-Based Disposable Electrochemical Sensor for Sensitive and Selective Determination of Ethyl Carbamate

Author:
Zhao, Xiaoyu, Zuo, Juanjuan, Qiu, Shue, Hu, Wenshuai, Wang, Yanfei, Zhang, Juankun
Source:
Food analytical methods 2017 v.10 no.10 pp. 3329-3337
ISSN:
1936-9751
Subject:
analytical methods, beverages, biomimetics, carcinogens, electrochemistry, electrodes, ethyl carbamate, fermented foods, graphene, impedance, mutagens, sensors (equipment)
Abstract:
Ethyl carbamate (EC), a multi-site genotoxic carcinogen, exists in fermented food and beverages. However, the existing analytical methods need precise instrument, complex sample pretreatment, time-consuming, and high cost. Therefore, a disposable electrochemical biomimetic sensor was developed for fast and selective detection of EC based on reduced graphene oxide/screen-printed carbon composite electrode (rGO/SPCE). Firstly, the SPCE is modified with rGO by electrodeposition process that increased current signal and decreased the impedance of contact interface. Secondly, the OAP/rGO/SPCE biomimetic sensor was synthesized through electropolymerization by cyclic voltammograms in mixed solution of template of EC and monomer of O-aminophenol (OAP). The sensor specifically bound to EC quickly without sample pretreatment. A linear range was from 100 to 1300 nM, and a detection limit of 37 nM was achieved. The detection time is less than 5 min. The sensor possesses advantages include good chemical and mechanical stability, simplicity, low cost of preparation, and sensitive and label-free determination. Graphical abstract Schematic diagram of preparation of rGO-SPCE based sensor
Agid:
5798390