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Regioselective Rh-Catalyzed Hydroformylation of 1,1,3-Trisubstituted Allenes Using BisDiazaPhos Ligand

Author:
Eshon, Josephine, Landis, Clark R., Schomaker, Jennifer M.
Source:
Journal of organic chemistry 2017 v.82 no.18 pp. 9270-9278
ISSN:
1520-6904
Subject:
aldehydes, catalysts, chemical structure, hydrogenation, isomerization, ligands, organic chemistry, regioselectivity
Abstract:
The efficient hydroformylation of 1,1,3-trisubstituted allenes is accomplished with low loadings of a Rh catalyst supported by a BisDiazaPhos (BDP) ligand. The ligand identity is key to achieving high regioselectivity, while the mild reaction conditions minimize competing isomerization and hydrogenation to produce β,γ-unsaturated aldehydes and their derivatives in excellent yields.
Agid:
5802978