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The Ribosome Holds the RNA Polymerase on Track in Bacteria

Author:
Klaholz, Bruno P.
Source:
Trends in biochemical sciences 2017 v.42 no.9 pp. 686-689
ISSN:
0968-0004
Subject:
DNA-directed RNA polymerase, bacteria, molecular biology, ribosomes, transcription (genetics), translation (genetics)
Abstract:
The central dogma of molecular biology comprises two fundamental mechanistic steps of gene expression (transcription and translation), which, in bacteria, are coupled. A recent study provides structural insights into a supercomplex between the RNA polymerase and the ribosome, thus highlighting the synergy between two key macromolecular machineries in the cell.
Agid:
5813031