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Design of Wall-Destructive but Membrane-Compatible Solvents

Author:
Kuroda, Kosuke, Satria, Heri, Miyamura, Kyohei, Tsuge, Yota, Ninomiya, Kazuaki, Takahashi, Kenji
Source:
Journal of the American Chemical Society 2017 v.139 no.45 pp. 16052-16055
ISSN:
1520-5126
Subject:
Escherichia coli, cell walls, cellulose, ethanol, fermentation, hydrolysis, liquids, solvents, viability, zwitterions
Abstract:
We report an extremely biocompatible solvent for plant cell walls based on a polar liquid zwitterion that dissolves cellulose, the most recalcitrant component of the plant cell walls. The polar liquid zwitterion does not affect the viability and activity of Escherichia coli, even at high concentrations. We demonstrate conversion of cell walls to ethanol via a starch-like process, namely successive dissolution, hydrolysis and fermentation in the same reaction pot.
Agid:
5860367