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Ambient mass spectrometry: Direct analysis of dimethoate, tebuconazole, and trifloxystrobin on olive and vine leaves by desorption electrospray ionization interface

Mainero Rocca, Lucia, Cecca, Juri, L'Episcopo, Nunziata, Fabrizi, Giovanni
Journal of mass spectrometry 2017 v.52 no.11 pp. 709-719
Olea europaea, Vitis vinifera, agrochemicals, dermal exposure, desorption, detection limit, dimethoate, exposure assessment, ionization, leaves, mass spectrometry, monitoring, occupational exposure, olives, quantitative analysis, solvents, tebuconazole, trifloxystrobin, vines
A new field of application for a relatively new mass‐spectrometric interface such as desorption electrospray ionization was evaluated. For this purpose, its behavior was tested versus quantitative analysis of dimethoate, trifloxystrobin, and tebuconazole directly on olive and vine leaves surface. The goal was workers exposure assessment during field re‐entry operations since evidence suggests an association between chronic occupational exposure to some agrochemicals and severe adverse effects. Desorption electrospray ionization gave good response working in positive ionization mode, while numerous test were necessary for the choice of a unique blend of spray solvents suitable for all 3 substances. The best compromise, in terms of signal to noise ratios, was obtained with the CH₃OH/H₂O (80:20) mixture. The obvious difficulties related to the impossibility to use the internal standard were overcome through an accurate validation. Limits of detection and quantitation, dynamic ranges, matrix effects, and intraday precisions were calculated, and a small monitoring campaign was arranged to test method applicability and to evaluate potential dermal exposure. This protocol was developed in work safety field, but after a brief investigation, it was find to be suitable also for food residue evaluation.