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13C Satellite-Free 1H NMR Spectra

Author:
Moutzouri, Pinelopi, Kiraly, Peter, Phillips, Andrew R., Coombes, Steven R., Nilsson, Mathias, Morris, Gareth A.
Source:
Analytical chemistry 2017 v.89 no.22 pp. 11898-11901
ISSN:
1520-6882
Subject:
carbon, filtration, nuclear magnetic resonance spectroscopy, stable isotopes
Abstract:
A new NMR experiment (Destruction of Interfering Satellites by Perfect Echo Low-pass filtration, DISPEL) is introduced that facilitates the analysis of low-level components in high dynamic range mixtures by suppressing one-bond ¹³C satellite signals in ¹H spectra. Since the natural abundance of ¹³C is around 1.1%, these satellites appear at 0.54% of the intensity of a parent peak, mimicking and often masking impurity signals. The new experiment suppresses one-bond ¹³C satellite signals, with high efficiency, at negligible cost in signal-to-noise ratio, and over a wide range of one-bond coupling constants, without the need for broadband ¹³C decoupling.
Agid:
5864074