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Phytochemical components and biological activities of Silene arenarioides Desf.

Author:
Golea, Lynda, Benkhaled, Mohammed, Lavaud, Catherine, Long, Christophe, Haba, Hamada
Source:
Natural product research 2017 v.31 no.23 pp. 2801-2805
ISSN:
1478-6427
Subject:
2,2-diphenyl-1-picrylhydrazyl, Silene, aerial parts, antioxidant activity, apigenin, chromatography, chrysin, electrospray ionization mass spectrometry, glucosides, inhibitory concentration 50, maltol, methanol, nuclear magnetic resonance spectroscopy, quercetin, stigmasterol
Abstract:
In this study, six known compounds 1 – 6 were isolated from the aerial parts of Silene arenarioides Desf . using different chromatographic methods. The structures of these compounds were identified as maltol glycoside (1), soyacerebroside I (2), chrysin (3), apigenin (4), quercetin (5) and stigmasterol glucoside (6). The compounds (1) and (2) are reported for the first time from this genus. The isolated compounds were determined using NMR techniques (¹H NMR, ¹³C NMR, COSY, HSQC and HMBC) and mass spectroscopy (ESI-MS). The antibacterial and antioxidant activities of extracts and of compound (1) have been evaluated. The antioxidant activity was performed by DPPH radical scavenging method, which showed that methanol extract possesses a good antioxidant activity with value of IC ₅₀ = 8.064 ± 0.005 μg/mL.
Agid:
5865391