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A New Amide and Antioxidant Constituents of Piper taiwanense

Author:
Chen, Jih-Jung, Wang, Shih-Wei, Chen, Chun-Lin, Kuo, Yueh-Hsiung, Cheng, Ming-Jen, Chang, Tsung-Hsien, Sung, Ping-Jyun, Kuo, Wen-Lung, Lim, Yun-Ping
Source:
Chemistry of natural compounds 2017 v.53 no.6 pp. 1117-1121
ISSN:
0009-3130
Subject:
2,2-diphenyl-1-picrylhydrazyl, Piper, aerial parts, alkaloids, antioxidant activity, decolorization, free radical scavengers, plant extracts, spectroscopy, vitamin content
Abstract:
A new amide, pipertaiwanamide (1), has been isolated from the aerial part of Piper taiwanense, together with four known compounds, taiwanamide A (2), taiwanamide B (3), 1-cinnamoylpyrrolidine (4), and N-cinnamoyltyramine (5). The structure of the new compound 1 was determined through spectroscopic and MS analyses. Pipertaiwanamide (1) and N-cinnamoyltyramine (5) exhibited free radical scavenging activity, with IC₀.₂₀₀ values of 12.6 ± 1.4 and 8.5 ± 0.8 𝜇M, respectively, in the diphenylpicrylhydrazyl radical (DPPH) decoloration assay.
Agid:
5867244