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A New Sydonic Acid Derivative From a Marine Derived-Fungus Aspergillus sydowii

Author:
Xiuli Xu, Shujiang Zhao, Liyuan Yin, Ying Yu, Zhengkun Chen, Huihui Shen, Li Zhou
Source:
Chemistry of natural compounds 2017 v.53 no.6 pp. 1056-1058
ISSN:
0009-3130
Subject:
Aspergillus, Candida albicans, Staphylococcus aureus, antibacterial properties, mass spectrometry, nuclear magnetic resonance spectroscopy, spectral analysis
Abstract:
Methyl (3-hydroxy-4-(2-hydroxy-6-methylheptan-2-yl)benzoyl)glycinate (1), a new sydonic acid derivative with glycinate, together with sydonic acid (2), sydowic acid (3), and 7-deoxy-7,14-didehydrosydonic acid (4), were isolated from a marine-derived Aspergillus sydowii strain CUGB-F126. Their structures were elucidated by spectroscopic analysis, including high-resolution mass spectroscopy, and 1D and 2D NMR techniques. All of these compounds did not show inhibitory activity against Staphylococcus aureus and Candida albicans.
Agid:
5867254