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Covalent and Ionic Conjugates of Trolox and α-Tocopherol with 1-Aminoadamantane

Author:
Yushkova, Yu.V., Morozov, S.V., Chernyak, E.I., Grigor’ev, I.A.
Source:
Chemistry of natural compounds 2017 v.53 no.6 pp. 1059-1065
ISSN:
0009-3130
Subject:
alpha-tocopherol, chemical bonding, mass spectrometry, nuclear magnetic resonance spectroscopy, water solubility
Abstract:
Covalent, ionic, and ionic-covalent conjugates of trolox and α-tocopherol with 1-aminoadamantane were synthesized. Their structures were elucidated using mass spectrometry and IR, PMR, and ¹³C NMR spectroscopy. The water solubility of the ionic trolox conjugates with 1-aminoadamantane increased by 2–24 times as compared with that of trolox whereas that of the α-tocopherol succinate conjugates remained the same as that of α-tocopherol.
Agid:
5867261