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Derivatisation for separation and detection in capillary electrophoresis (2015–2017)
- Wuethrich, Alain, Quirino, Joselito P.
- Electrophoresis 2018 v.39 no.1 pp. 82-96
- capillary electrophoresis, derivatization, separation
- Derivatisation is an integrated part of many analytical workflows to enable separation and detection of the analytes. In CE, derivatisation is adapted in the four modes of pre‐capillary, in‐line, in‐capillary, and post‐capillary derivatisation. In this review, we discuss the progress in derivatisation from February 2015 to May 2017 from multiple points of view including sections about the derivatisation modes, derivatisation to improve the analyte separation and analyte detection. The advancements in derivatisation procedures, novel reagents, and applications are covered. A table summarising the 46 reviewed articles with information about analyte, sample, derivatisation route, CE method and method sensitivity is provided.