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Evidence of porcine circovirus‐like virus P1 in piglets with an unusual congenital tremor

Author:
Wen, L., Mao, A., Jiao, F., Zhang, D., Xie, J., He, K.
Source:
Transboundary and emerging diseases 2018 v.65 no.2 pp. e501
ISSN:
1865-1674
Subject:
Classical swine fever virus, Porcine circovirus-2, blood serum, brain, emerging diseases, farms, genome, immunohistochemistry, livestock and meat industry, lymph nodes, piglets, quantitative polymerase chain reaction, China
Abstract:
Outbreaks of trembling and shaking were reported among pigs at two pig farms in Jiangsu Province, China. Serum and tissue samples tested positive for porcine circovirus‐like virus P1 and negative for classical swine fever virus, porcine circovirus type 2, astrovirus and porcine pestivirus using PCR/RT‐PCR and immunohistochemical techniques. High P1 viral genome loads were identified in sera, brain and lymph node tissue samples by qPCR. In addition, one of the most notable pathological changes was dissolution of the nucleus in Purkinje cells. The results of this study provide molecular evidence of an association between congenital tremor in pigs and P1 virus.
Agid:
5898436