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Addition of Cyanoethyl Groups to Ring a of Triterpenoids
- Galaiko, N.V., Tolmacheva, I.A., Igosheva, E.V., Savinova, O.V., Grishko, V.V.
- Chemistry of natural compounds 2018 v.54 no.2 pp. 305-309
- triterpenoids, moieties, Human alphaherpesvirus 1
- The potential for cyanoethylation of ring A of triterpenoids and their A-seco derivatives prepared from allobetulone and methyl betulonate was investigated. Triterpenoids with a cyanoethyl moiety on C-1, C-2, and C-3 and derivatives with two cyanoethyl groups on ring A were synthesized. The inhibitory activity of the synthesized compounds for herpes simplex virus type 1 was studied in vitro.