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Preparation, characterization and antioxidant activity of polysaccharide from Fallopia multiflora (Thunb.) Harald

Author:
Chen, Li, Zhang, Yipeng, Jin, Lixin, Gao, Renjiao, Bao, Jiaqi, Cui, Bowen
Source:
International journal of biological macromolecules 2018 v.108 pp. 259-262
ISSN:
0141-8130
Subject:
Reynoutria multiflora, antioxidant activity, blood serum, enzyme activity, free radicals, glucose, glutathione peroxidase, high performance liquid chromatography, humans, hydroxyl radicals, malondialdehyde, molecular weight, polysaccharides, superoxide dismutase
Abstract:
This study aimed to investigate antioxidant activities of a polysaccharide from Fallopia multiflora (Thunb.) Harald. F. multiflora polysaccharide (FMP) was prepared and partially characterized by high performance liquid chromatography, fourier transform infrared spectrum and anion chromatography, and its antioxidant activities both in vitro and in vivo were investigated. FMP, with a molecular weight of 17,758Da consisted of glucose. In vivo, FMP had high hydroxyl radical scavenging activity and reducing capacity. In vivo, FMP increased serum superoxide dismutase and glutathione peroxidise activities and decreased the level of malondialdehyde. These results indicated that FMP exhibits high antioxidant activity both in vitro and in vivo and might retard human ageing associated with free radicals.
Agid:
5933945