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The Cytokinin-Activating LOG-Family Proteins Are Not Lysine Decarboxylases

Author:
Naseem, Muhammad, Bencurova, Elena, Dandekar, Thomas
Source:
Trends in biochemical sciences 2018 v.43 pp. 232-236
ISSN:
0968-0004
Subject:
cytokinins, enzyme activity, enzymes, lysine, nucleotides, proteins
Abstract:
A conserved PGGxGTxxE motif misleads the cytokinin (CK) converting LONELY GUY enzymes to be wrongly annotated as lysine decarboxylases (LDCs). However, so far PGGxGTxxE motif-containing LDCs do not show any LDC activity. Instead, they show phosphoribohydrolase activity by converting inactive CK nucleotides into active free-base forms to invoke CK responses.
Agid:
5937535