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Factors affecting the quantitative uncertainty of the estimated short-term intake. Part I—Calculation methods Part B Pesticides, food contaminants, and agricultural wastes

Ambrus, Árpád, Horváth, Zsuzsanna, Szenczi-Cseh, Júlia, Szabó, István J.
Journal of environmental science and health 2018 v.53 no.6 pp. 394-403
Food and Agriculture Organization, World Health Organization, apples, equations, ethephon, food safety, maximum residue limits, pesticide residues, public health, uncertainty
The calculation of the combined uncertainty of the international estimated short-term intake (IESTI) of ethephon residues in apples is shown as an example. The ethephon residues in apples were reported by the Joint FAO (Food and Agriculture Organization of the United Nations)/WHO (World Health Organization) Meeting on Pesticide Residues (JMPR). The apple consumption data were taken from the IESTI (international short-term intake) calculation template used by the JMPR. The IESTI was calculated with the currently used method (case 2a) and a proposed one recommended by the EFSA (European Food Safety Authority)/RIVM (Dutch National Institute for Public Health) Scientific Workshop co-sponsored by FAO and WHO. In this example, the ratio of IESTIₚᵣₒₚₒₛₑd/IESTIcᵤᵣᵣₑₙₜ and their combined relative uncertainty are about 2.8, and 1.7, respectively. The larger IESTI and uncertainty obtained with the proposed equation are the consequence of calculation only with the large portion (LP) instead of its combination with unit mass, and the MRL instead of the highest residue (HR). The LP is the major contributor to the combined uncertainty. Both the calculated IESTI and its combined uncertainty depend on the actual food – pesticide residue combination, and should be calculated for each case.