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Probiotic Potential of Pediococcus pentosaceus LJR1, a Bacteriocinogenic Strain Isolated from Rumen Liquor of Goat (Capra aegagrus hircus)

Ladha, Gothandam, Jeevaratnam, Kadirvelu
Food biotechnology 2018 v.32 no.1 pp. 60-77
Capra hircus aegarus, Lactobacillus rhamnosus, Listeria monocytogenes, Pediococcus pentosaceus, adhesion, anti-inflammatory activity, antibacterial properties, bile, colorectal neoplasms, food pathogens, foods, goats, humans, mononuclear leukocytes, probiotics, rumen fluids
In present study, we evaluated the probiotic potential of three potent antibacterial Pediococcus pentosaceus isolates, viz., LJR1, LJR5, and LJR9 from the rumen liquor of a healthy goat and compared to a commercial probiotic, Lactobacillus rhamnosus GG NCDC 347. All the three isolates exhibited broad-spectrum of antibacterial activity against food borne pathogens. Among the isolates P. pentosaceus LJR1 strain was found to tolerate acid, bile, simulated gastric, and intestinal juice comparable to a standard strain and also showed strong adhesion to the human colon cancer (HCT-15) cells and prevented adhesion of Listeria monocytogenes. Furthermore, the P. pentosaceus LJR1 showed strong anti-inflammatory properties in the LPS-inflamed human peripheral blood mononuclear cells (PBMCs). The P. pentosaceus LJR1 showing potent antibacterial activity and all the desirable attributes of probiotic bacteria can be utilized as a candidate for the development of probiotic foods and deserves to be exploited for human and animal use.