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Probiotic Potential of Pediococcus pentosaceus LJR1, a Bacteriocinogenic Strain Isolated from Rumen Liquor of Goat (Capra aegagrus hircus)

Author:
Ladha, Gothandam, Jeevaratnam, Kadirvelu
Source:
Food biotechnology 2018 v.32 no.1 pp. 60-77
ISSN:
1532-4249
Subject:
Capra hircus aegarus, Lactobacillus rhamnosus, Listeria monocytogenes, Pediococcus pentosaceus, adhesion, anti-inflammatory activity, antibacterial properties, bile, colorectal neoplasms, food pathogens, foods, goats, humans, mononuclear leukocytes, probiotics, rumen fluids
Abstract:
In present study, we evaluated the probiotic potential of three potent antibacterial Pediococcus pentosaceus isolates, viz., LJR1, LJR5, and LJR9 from the rumen liquor of a healthy goat and compared to a commercial probiotic, Lactobacillus rhamnosus GG NCDC 347. All the three isolates exhibited broad-spectrum of antibacterial activity against food borne pathogens. Among the isolates P. pentosaceus LJR1 strain was found to tolerate acid, bile, simulated gastric, and intestinal juice comparable to a standard strain and also showed strong adhesion to the human colon cancer (HCT-15) cells and prevented adhesion of Listeria monocytogenes. Furthermore, the P. pentosaceus LJR1 showed strong anti-inflammatory properties in the LPS-inflamed human peripheral blood mononuclear cells (PBMCs). The P. pentosaceus LJR1 showing potent antibacterial activity and all the desirable attributes of probiotic bacteria can be utilized as a candidate for the development of probiotic foods and deserves to be exploited for human and animal use.
Agid:
5953380