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Phytochemical, cytotoxic and chemotaxonomic study on Ajuga forrestii Diels (Labiatae)

Author:
Chen, Tong, Diao, Qing-Yan, Yu, Hai-Zhou, Jiao, Chun-Li, Ruan, Jian
Source:
Natural product research 2018 v.32 no.8 pp. 977-981
ISSN:
1478-6427
Subject:
Ajuga, chemotaxonomy, cytotoxicity, diterpenoids, iridoid glycosides, phytoecdysteroids, spectroscopy
Abstract:
A phytochemical investigation of Ajuga forrestii Diels led to the isolation of 14 compounds, including eight neo-clerodane diterpenes (1–8), two phytoecdysteroids (9, 11), one stigmastane sterol (10) and three iridoid glycosides (12–14). The structures of these compounds were identified by spectroscopic methods and a comparison of their data with those reported in the literature. This is the first report of compounds 1–14 from A. forrestii. The cytotoxic activities of the aqueous extract of A. forrestii and several compounds have been studied and the chemotaxonomic significance of isolated compounds has also been summarised.
Agid:
5953999