Main content area

Antimould microbial and plant metabolites with potential use in intelligent food packaging

Valerio, Francesca, Masi, Marco, Cimmino, Alessio, Moeini, Seyed Arash, Lavermicocca, Paola, Evidente, Antonio
Natural product research 2018 v.32 no.13 pp. 1605-1610
Aspergillus niger, Penicillium roquefortii, biodegradability, biofilm, biopesticides, financial economics, food packaging, fungi, human health, metabolites, microbial growth, minimum inhibitory concentration
Moulds food infestation is a heavy dangerous problem for human health and also could generate heavy economic losses. The intelligent packaging using eco-friendly biodegradable biofilm incorporating bioactive natural safe compounds represents a new frontier. This manuscript reports the inhibitory activity of 12 bacterial, fungal and plant metabolites against Penicillium roqueforti and Aspergillus niger. Among them α-costic acid and ungeremine (3 and 12) are the most promising as potential biofungicide against both fungal strains. They inhibited fungal growth by more than 60% respect to the control at 72 h and this activity persisted also at 96 h. Ungeremine showed MIC₉₀ lower than 0.003 mg/mL after 48 h of incubation and of 0.025 mg/mL at 72 h against P. roqueforti. The MIC₉₀ value for A. niger was 0.2 mg/mL at 48 h for both compounds. The α-costic acid showed generally MIC values at 48 and 72 h higher than ungeremine.