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Two new hirsutane-type sesquiterpenoids chondrosterins N and O from the marine fungus Chondrostereum sp.

Author:
Huang, Lei, Lan, Wen-Jian, Li, Hou-Jin
Source:
Natural product research 2018 v.32 no.13 pp. 1578-1582
ISSN:
1478-6427
Subject:
Chondrostereum, Sarcophyton, corals, culture media, ethyl acetate, marine fungi, metabolites, moieties, nuclear magnetic resonance spectroscopy, sesquiterpenoids, South China Sea
Abstract:
The marine fungus Chondrostereum sp. was collected from a soft coral Sarcophyton tortuosum from the South China Sea. This fungus was cultured in glucose-peptone-yeast (GPY) medium and the culture broth was extracted with EtOAc. By the method of ¹H NMR pre-screening and tracing the diagnostic proton signals of the methyl groups, two new hirsutane-type sesquiterpenoids, chondrosterins N and O (1 and 2) were isolated from the metabolite extracts. Their structures were elucidated on the basis of MS, 1D and 2D NMR data.
Agid:
5954041