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A new 12,17-cyclo-labdane diterpenoid from the twigs of Dacrycarpus imbricatus
- Yang, Zuofa, Wang, Qiuxiang, Peng, Wei, Zhan, Rui, Chen, Yegao
- Natural product research 2018 v.32 no.14 pp. 1669-1675
- Dacrycarpus imbricatus, branches, diterpenoids, humans, neoplasms, spectral analysis
- A new 12,17-cyclo-labdane diterpenoid, podoimbricatin C (1), along with 15 known compounds was isolated from the twigs of Dacrycarpus imbricatus. Their structures were elucidated by means of extensive spectroscopic analysis. Compound 1 is the second example of the unusual 12,17-cyclo-labdane diterpenoids. It showed no inhibitory effects against five human tumour lines (HL-60, SMMC-7721, A-549, MCF-7 and SW-480).