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Panoply of Fluorescence Polarization/Anisotropy Signaling Mechanisms for Functional Nucleic Acid-Based Sensing Platforms

Author:
Perrier, Sandrine, Guieu, Valérie, Chovelon, Benoit, Ravelet, Corinne, Peyrin, Eric
Source:
Analytical chemistry 2018 v.90 no.7 pp. 4236-4248
ISSN:
1520-6882
Subject:
anisotropy, antibodies, fluorescence, immunoassays, nucleic acids
Abstract:
Fluorescence polarization/anisotropy is a very popular technique that is widely used in homogeneous-phase immunoassays for the small molecule quantification. In the present Feature, we discuss how the potential of this signaling approach considerably expanded during the last 2 decades through the implementation of a myriad of original transducing strategies that use functional nucleic acid recognition elements as a promising alternative to antibodies.
Agid:
5986046