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1,4-Addition of aryl boronic acids to α,β-unsaturated ketones catalyzed by a CCC–NHC pincer rhodium complex

Author:
Reilly, Sean W., Box, Hannah K., Kuchenbeiser, Glenn R., Rubio, Ramel J., Letko, Christopher S., Cousineau, Kandarpa D., Hollis, T. Keith
Source:
Tetrahedron letters 2014 v.55 no.49 pp. 6738-6742
ISSN:
0040-4039
Subject:
aldehydes, boronic acids, chemical reactions, chemical structure, ketones, methanol, rhodium, solvents
Abstract:
An air- and water-stable CCC–NHC pincer Rh complex catalyzed the 1,4-addition of aryl boronic acids to α,β-unsaturated ketones and aldehydes. This bench top method proceeds in eco-friendly solvents including methanol and water. The scope of boronic acids was expanded to include heterocyclic examples.
Agid:
5995482