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An efficient protocol for domino one pot synthesis of 1,2,3-triazoles from natural organic acids and phenols

Author:
Dangroo, Nisar A., Dar, Alamgir A., Dar, Bashir Ahmad
Source:
Tetrahedron letters 2014 v.55 no.49 pp. 6729-6733
ISSN:
0040-4039
Subject:
catalysts, chemical reactions, chemical structure, organic acids and salts, phenols, protocols, synthesis, triazoles
Abstract:
An efficient three-component protocol was developed for the one-pot synthesis of 1,2,3-triazoles from natural product based acids and phenols, using CuSO4–sodium ascorbate catalyst system. The method is general and showed considerable synthetic advantage giving products in excellent yields with a wide substrate scope.
Agid:
5995498