U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

Molecular characterization of the complete genome of falconid herpesvirus strain S-18

Author:
Stephen J. Spatz, Jeremy D. Volkening, Teresa A. Ross
Source:
Virus Research 2014 v.188 pp. 109-121
ISSN:
0168-1702
Subject:
mutation, viral proteins, genes, monophyly, nucleotide sequences, Anatid alphaherpesvirus 1
Abstract:
Falconid herpesvirus type 1 (FaHV-1) is the causative agent of falcon inclusion body disease, an acute, highly contagious disease of raptors. The complete nucleotide sequence of the genome of FaHV-1 has been determined using Illumina MiSeq sequencing. The genome is 204,054 nucleotides in length and has a class E organization. The genome encodes approximately 130 putative protein-coding genes, of which70 are orthologs of conserved alphaherpesvirus and Mardivirus proteins. Three FaHV-1 genes (UL3.5,UL44.5 and CIRC) were identified that encode protein homologues unique to Mardivirus and Varicellovirus.The genome also encodes homologues to the Mardivirus genes LORF2, LORF3, LORF4, LORF5, SORF3 andSORF4. An opal mutation resulting in premature termination was identified in the FaHV-1 UL43 gene. Phylogenetically, FaHV-1 resides in a monophyletic group with the other Mardiviruses but, along with anatid herpesvirus 1, represents a more distant divergence from the rest of the Mardivirus genus.
Agid:
60114
Handle:
10113/60114