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Different oils used as supplement during lactation causes endocrine-metabolic dysfunctions in male rats
- Quitete, Fernanda Torres, Lisboa, Patricia C., de Moura, Egberto Gaspar, de Oliveira, Elaine
- Journal of functional foods 2018 v.48 pp. 43-53
- cholesterol, coconut oil, fish, fish oils, lactation, males, metabolism, milk, milk composition, obesity, olive oil, olives, overeating, progeny, pups, rats, soybean oil, soybeans, triacylglycerols, weaning
- Some oils considered healthy are commonly used, even in critical periods of life. We studied the effects of maternal supplementation with soybean, olive, fish and coconut oils during lactation on the male rat offspring metabolism. Dams and pups were divided: Soybean oil (control); Olive Oil (OO); Fish Oil (FO) and Coconut Oil (CO). Dams received the oils through gavage (0.5 g/kg BW) during lactation, as a supplement. At weaning, OO pups showed obesity. Milk from CO dams presented higher triglycerides. Milk from OO and CO dams presented more cholesterol and calories. At weaning, FO and CO pups presented hypotriglyceridemia. At PN180, OO and CO offspring showed obesity and hyperleptinemia. OO offspring had higher lean mass. CO offspring presented hyperphagia. OO, FO and CO offspring had higher T3. Oils used as supplement during lactation alter milk composition and induces short and long-term endocrine-metabolic dysfunctions in the progeny.