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A diastereoselective synthesis of functionalized bis-spirorhodanine-linked cyclopentanes via C(sp3)–H activation

Author:
Yavari, Issa, Naeimabadi, Maryam, Halvagar, Mohammad R.
Source:
Tetrahedron 2018
ISSN:
0040-4020
Subject:
X-ray diffraction, chemical structure, cycloaddition reactions, diastereoselective synthesis, iodine, pyridines
Abstract:
A diastereoselective synthesis of bis-spirorhodanine-linked cyclopentane derivatives via the [2 + 2+1] cycloaddition reaction between alkyl (Z)-2-(3-alkyl-4-oxo-2-thioxothiazolidin-5-ylidene)acetates (alkylidenerhodanines) and azomethine ylides, prepared in situ from iodine mediated reaction of 2-methylquinoline and pyridine in the presence of base, has been developed. The structure of a typical product was confirmed by X-ray crystallography.
Agid:
6018088