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Intramolecular sulfonylamidomethylation of 2-(2-naphthyl) and 2-(1-naphthyl)ethanesulfonamides: synthesis of new class of naphthosultams

Author:
Sasiambarrena, Leandro D., Cánepa, Alicia S., Luna, Constanza N., Bravo, Rodolfo D.
Source:
Tetrahedron letters 2015 v.56 no.16 pp. 2054-2058
ISSN:
0040-4039
Subject:
catalysts, chemical reactions, chemical structure, organic compounds, regioselectivity
Abstract:
New 1,2,4,5-tetrahydronaphtho[1,2-d]3,2-thiazepine 3,3-dioxides and 1,2,4,5-tetrahydronaphtho[2,1-d]3,4-thiazepine 3,3-dioxides were synthesized by aromatic intramolecular sulfonylamidomethylation of 2-(2-naphthyl) and 2-(1-naphthyl)ethanesulfonamides with s-trioxane using Amberlyst XN-1010 as catalyst in excellent yields and with high regioselectivity.
Agid:
6025246