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Cybastacines A and B: Antibiotic Sesterterpenes from a Nostoc sp. Cyanobacterium
- Cabanillas, Alfredo H., Tena Pérez, Víctor, Maderuelo Corral, Santiago, Rosero Valencia, Diego Fernando, Martel Quintana, Antera, Ortega Doménech, Montserrat, Rumbero Sánchez, Ángel
- Journal of natural products 2018 v.81 no.2 pp. 410-413
- Nostoc, X-ray diffraction, antibacterial properties, antibiotics, guanidinium, spectral analysis, Canary Islands
- Cybastacines A (1) and B (2) were discovered as a novel pentacyclic sesterterpenoid–alkaloid skeleton structure, with a guanidinium group. These molecules were isolated from a Nostoc sp. cyanobacterium collected in the Canary Islands. Their structures were elucidated primarily by a combination of spectroscopic analyses and X-ray diffraction. These compounds showed antibiotic activities against several clinically relevant bacterial strains.