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Natural Products Containing a Nitrogen–Sulfur Bond

Author:
Petkowski, Janusz J., Bains, William, Seager, Sara
Source:
Journal of natural products 2018 v.81 no.2 pp. 423-446
ISSN:
1520-6025
Subject:
amino acids, bioactive properties, biosynthesis, chemical bonding, moieties, peptides, post-translational modification, proteins
Abstract:
Only about 100 natural products are known to contain a nitrogen–sulfur (N–S) bond. This review thoroughly categorizes N–S bond-containing compounds by structural class. Information on biological source, biological activity, and biosynthesis is included, if known. We also review the role of N–S bond functional groups as post-translational modifications of amino acids in proteins and peptides, emphasizing their role in the metabolism of the cell.
Agid:
6043092