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Effects of prebiotic inulin addition to low- or high-fat diet on maternal metabolic status and neonatal traits of offspring in a pregnant sow model

Zhou, Pan, Wang, Yongsheng, Li, Shuang, Zhao, Yang, Deng, Kai, Chao, Dandan, Jin, Chao, Zhuo, Yong, Che, Lianqiang, Li, Jian, Lin, Yan, Xu, Shengyu, Feng, Bin, Fang, Zhengfeng, Wu, De
Journal of functional foods 2018 v.48 pp. 125-133
bile acids, blood lipids, blood serum, body mass index, butyrates, calcium, digestibility, excretion, glucose tolerance, high fat diet, insulin resistance, inulin, lipid composition, models, piglets, prebiotics, pregnancy, progeny, propionic acid, sows
The effects of adding inulin to low- or high-fat diet on the metabolic status and nutrient digestibility in gestating sows and the neonatal traits of their offspring were examined. Sixty sows were allocated to a 2 × 2 factorial treatment design with levels of inulin (0% or 1.5%) and fat (0% or 5%) addition as the fixed factors during gestation. Inulin supplementation resulted in the following: improved serum lipid profiles, insulin resistance, and glucose tolerance, which were adversely impacted by fat addition; increased serum butyrate concentration throughout gestation and propionate concentration on day 60 of gestation when given with a high-fat diet; enhanced fecal bile acid excretion in a high-fat diet; lowered ether extract (EE) digestibility and increased calcium digestibility in the sow; and decreased BMI and carcass EE content in neonatal piglets. The beneficial effects of inulin were particularly marked when it was combined with a high-fat diet.