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Photoelectrochemical aptasensing

Author:
Zhao, Wei-Wei, Xu, Jing-Juan, Chen, Hong-Yuan
Source:
Trends in analytical chemistry 2016 v.82 pp. 307-315
ISSN:
0165-9936
Subject:
antibodies, binding properties, nucleic acids, oligonucleotides
Abstract:
Photoelectrochemical (PEC) bioanalysis represents a unique and dynamically developing methodology that offers an elegant route for sensitive biomolecular detection. Aptamers are synthetic nucleic acid molecules whose binding characteristics can rival those of protein antibodies. Originated from the fusion of PEC bioanalysis and aptamers, PEC aptasensing has rapidly becoming a subject of new research interests in recent years. Using illustrative examples, this review provides the introductory concept, bioanalysis development, signaling strategies, and the state of the art in this field. The future prospects are also discussed.
Agid:
6066891