Jump to Main Content
Synthesis of optically active macrolides with hydrazide fragments from tetrahydropyran and L-(+)-tartaric acid derivatives
- Ishmuratov, G. Yu., Yakovleva, M. P., Mingaleeva, G. R., Shutova, M. A., Muslukhov, R. R., Vyrypaev, E. M., Tolstikov, A. G.
- Chemistry of natural compounds 2013 v.49 no.4 pp. 691-693
- acids, hydrazides, macrolides, synthesis
- The synthesis of two potentially useful optically active 23- and 30-membered macrolides containing a 1,2-diol system and dihydrazide fragments was developed starting from tetrahydropyran. It was based on [1+1]-condensation of 7-oxooctyl-7-oxooctanoate and bis(7-oxooctyl)hexanedioate with L-(+)-tartaric acid hydrazide.