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Copper(I)-Catalyzed Three-Component Click/Persulfuration Cascade: Regioselective Synthesis of Triazole Disulfides

Author:
Wang, Weiguo, Lin, Yunzhi, Ma, Yudao, Tung, Chen-Ho, Xu, Zhenghu
Source:
Organic letters 2018 v.20 no.10 pp. 2956-2959
ISSN:
1523-7052
Subject:
chemical reactions, copper, moieties, regioselectivity, sulfides, triazoles
Abstract:
A copper(I)-catalyzed three-component CuAAC/persulfuration reaction providing rapid access to asymmetric triazole disulfides has been developed. The interrupted click reaction shows broad substrate scope, complete regioselectivity, and excellent functional group tolerability.
Agid:
6083947