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Mechanochemically synthesized Ag-based nanohybrids with unprecedented low toxicity in biomedical applications

Author:
Arancon, Rick A.D., Balu, Alina M., Romero, Antonio A., Ojeda, Manuel, Gomez, Mercedes, Blanco, Jordi, Domingo, Jose L., Luque, Rafael
Source:
Environmental research 2017 v.154 pp. 204-211
ISSN:
0013-9351
Subject:
biocompatibility, cytotoxicity, human cell lines, mechanochemistry, nanohybrids, nanosilver, silver
Abstract:
A simple and innovative mechanochemical approach was employed to synthesize Ag-polysaccharide nanohybrid materials that were proved to exhibit remarkable surface properties and structures for biomedical applications. The synthesized Ag nanomaterials possessed an unprecedented low cytotoxicity against human cell lines A549 and SH-SY5Y as compared to similarly reported Ag nanomaterials due to the stability and low release of Ag⁺ and high biocompatibility of the nanohybrids.
Agid:
6092507