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Subacute sclerosing panencephalitis mortality, United States, 1979–2016: Vaccine-induced declines in SSPE deaths

Author:
Pallivathucal, Lia B., Noymer, Andrew
Source:
Vaccine 2018 v.36 no.35 pp. 5222-5225
ISSN:
0264-410X
Subject:
Measles virus, measles, mortality, neurodegenerative diseases, vaccination, vaccines, United States
Abstract:
Subacute sclerosing panencephalitis (SSPE) is a neurodegenerative disease caused by measles virus. We estimate SSPE age-specific mortality in the United States, 1979–2016. The general decline in SSPE mortality reflects that of measles. Shifts, over time, in SSPE mortality by age echo changes in the age distribution of measles in the 1970s and in the 1989–91 outbreak. The current epidemiological situation is that autochthonous SSPE will disappear in the United States, assuming measles vaccination rates remain high.
Agid:
6102450