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Natural selenium particles from Staphylococcus carnosus: Hazards or particles with particular promise?

Author:
Estevam, Ethiene Castellucci, Griffin, Sharoon, Nasim, Muhammad Jawad, Denezhkin, Polina, Schneider, Ramona, Lilischkis, Rainer, Dominguez-Alvarez, Enrique, Witek, Karolina, Latacz, Gniewomir, Keck, Cornelia, Schäfer, Karl-Herbert, Kieć-Kononowicz, Katarzyna, Handzlik, Jadwiga, Jacob, Claus
Source:
Journal of hazardous materials 2017 v.324 pp. 22-30
ISSN:
0304-3894
Subject:
Escherichia coli, Staphylococcus carnosus, Steinernema feltiae, bacteria, cell death, coatings, medicine, microparticles, nanotechnology, selenites, selenium, thiols
Abstract:
Various bacteria, including diverse Staphylococci, reduce selenite to yield red selenium particles with diameters in the high nanometer to low micrometer range. Formation and accumulation of such particles in bacteria often results in cell death, triggered by a loss of thiols and formation of disruptive deposits inside the cell. Hence certain pathogenic bacteria are rather sensitive to the presence of selenite, whilst other organisms, such as small nematodes, do not employ this kind of nanotechnology, yet become affected by micromolar concentrations of such naturally generated materials. Selenium particles extracted from cultures of Staphylococcus carnosus and apparently stabilized by their natural protein coating, for instance, show considerable activity against the nematode Steinernema feltiae, Escherichia coli and Saccaromyces cerevisiae. Such natural nano- and micro-particles are also more active than mechanically generated selenium particles and may be applied as antimicrobial materials in Medicine and Agriculture.
Agid:
6106831